Author(s): Warmerdam CAR; Westra HJ; van der Graaf A; Bonder MJ; Deelen P; van Lieshout T; Landman AJ; Jesse M; Strober BJ; Boltz T; Lapinska S; Nagpal S; Xie M; Tay D; Kirsten H; Naeem H; Raghavan V; Farzeen A; Teumer A; Favé MJ; Persyn E; Tokolyi ...

Many non-coding variants influence complex traits and diseases through gene regulation, yet the mechanisms linking these variants to downstream biology remain poorly understood. Here, we present eQTLGen Phase 2, a comprehensive genome-wide analysis of gene expression quantitative trait loci (eQTL ...

Article GUID: 42051578

Author(s): Kapasa RL; Grenon C; Berbiche D; Gouin JP; Vena JE; Vasiliadis HM;

Aims: This study identified sex-specific multi-trajectories of anxiety and depression symptoms among Canadians before and during the COVID-19 pandemic, and associated factors according to a public mental health framework for the surveillance of mental health. Methods: Data from 15,021 participants in the Canadian Partnership for Tomorrow's Health coh ...

Article GUID: 42107659

Author(s): Korte JA; Steele CJ; Joiner WM; Fan AP;

There is a growing interest to study cerebellar contributions to aging outside of traditional sensory processing and motor tasks. While cerebellar aging analyses typically utilize functional connectivity (FC) to study functional differences with age, this study aimed to identify a marker of healthy aging based on resting state blood oxygenation level depe ...

Article GUID: 42108695

Author(s): Rosenstein B; Bergevin M; Bobeuf F; Bherer L; Pageaux B; Roy M; Fortin M;

Background: Multimodal exercise programs do not specifically target lumbar paraspinal musculature, but incorporate aspects of different exercises to have an overall benefit. Objective: To investigate the effect of a multimodal exercise program on paraspinal muscle volume and composition, and patient outcomes in individuals with chronic low back pain (CLB ...

Article GUID: 42093855

Author(s): Marquez M; Lai Y; Liu M; Memari E; Helfield B; Liang J;

Real-time dynamic imaging of microbubbles is crucial for understanding their microscale biophysical interactions and advancing ultrasound therapy. Despite progress in time-resolved optical imaging, existing techniques still face trade-offs between acquisition speed, spatial resolution, affordability, and system complexity. Here, we introduce compressed op ...

Article GUID: 42078858

Author(s): Shojaei S; Mulligan CN;

Biosurfactants offer a green, sustainable approach to many environmental bioremediations, especially for oil contamination. In this study, the aim is to evaluate the effectiveness of biosurfactants in accelerating hydrocarbon removal from mature fine tailings under anaerobic conditions. The bacteria were isolated from mature fine tailings and tested for b ...

Article GUID: 42072246

Author(s): Vishweswariah K; Ningappa NG; Kumar M R A; Dawkins JIG; Selva TMG; Zaghib K;

Separators have evolved from passive polymeric barriers into multifunctional components that critically govern the performance, safety, and lifetime of liquid and quasi-solid lithium rechargeable batteries. This Review provides a comprehensive analysis of separator materials and architectures spanning commercial polyolefins and their ceramic coatings, hig ...

Article GUID: 42015518

Author(s): Harsanyi H; Slot N; Parkinson R; Morielli AR; Jeyapalan A; Holmes E; Flynn S; Campbell T; Quan H; Zeng Y; Yang J; Singh S; Vena J; Biddle S; Friedenreich CM; Yang L;

Article GUID: 42015269

Author(s): Sajedi S; An C;

The widespread use of single-use plastic (SUP) water bottles has raised growing concerns about chronic human exposure to nanoplastics (NPs). This study presents a quantitative assessment of NP accumulation in human tissues resulting from the long-term consumption of SUP water bottles. Using survey-derived consumption data and the Human Exposure and Absorp ...

Article GUID: 42007012

Author(s): Gilbert W; Stack DM; Barker ET; Dubeau A; Serbin LA; Véronneau MH;

Given the high prevalence of psychological distress among vocational training (VT) students, this study aimed to assess the role of interpersonal emotional competence as a resilience factor promoting the educational success of this population. We postulated that emotional competence would promote educational success, both directly and indirectly by foster ...

Article GUID: 42005820

Author(s): Kafian Safari M; Mirzae M; Gheflati B; Sharifzade M; Zuhars J; Rottoo S; Rivaz H;

Purpose: Computer- and robotic-assisted technologies improve total knee arthroplasty (TKA) through intraoperative bone registration. However, limited bone exposure restricts point collection to the distal femur, omitting key geometric features and reducing registration accuracy and the surgical outcomes. Methods: We introduce a deep learning-based method ...

Article GUID: 41984365