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Transwell membrane material affects myogenic differentiation in human primary myoblast-adipocyte co-culture

Author(s): Plissonneau C; Tam BT; Garneau PY; Morais JA; Piekny A; Santosa S;

Transwell co-culture systems are models for examining cellular crosstalk, but the impact of porous membrane material on myogenic outcomes remains uncharacterized. We investigated the influence of transwell membrane material on myoblast differentiation in co-culture with human primary adipocytes and in varying concentrations of insulin-transferrin-seleni ...

Article GUID: 42260998


Regional primary preadipocyte characteristics in humans with obesity and type 2 diabetes mellitus

Author(s): Plissonneau C; Santosa S;

The excessive accumulation of adipose tissue in obesity appears to result in adipose tissue dysfunction perpetuating the onset of obesity-related diseases, including type 2 diabetes (T2DM). In humans, adipose tissue is stored in several depots including subcutaneous and visceral. These depots contribute to the pathology of obesity differently owing to d ...

Article GUID: 39553621


Factors associated with adipocyte size reduction after weight loss interventions for overweight and obesity: a systematic review and meta-regression.

Author(s): Murphy J, Moullec G, Santosa S

Metabolism. 2017 Feb;67:31-40 Authors: Murphy J, Moullec G, Santosa S

Article GUID: 28081776


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