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T cells are elevated in abdominal and femoral adipose tissue in females with type 2 diabetes

Author(s): Delaney KZ; Nadeem MI; Plissonneau C; Khor N; Delaney J; Morais JA; Tsoukas MA; Pescarus R; Garneau PY; Santosa S;

Adipose tissue (AT) immune cells are implicated in the pathology of type 2 diabetes (T2D), and their content likely differs between abdominal subcutaneous adipose tissue (abSAT), femoral SAT (fmSAT), and visceral adipose tissue (VAT). Therefore, the objective of the current study was to develop ...

Article GUID: 42255513


Effects of chronodisruption and alcohol consumption on gene expression in reward-related brain areas in female rats

Author(s): Meyer C; Schoettner K; Amir S;

Circadian dysfunction caused by exposure to aberrant light-dark conditions is associated with abnormal alcohol consumption in humans and animal models. Changes in drinking behavior have been linked to alterations in clock gene expression in reward-related brain areas, which could be attributed to either the effect of chronodisruption or alcohol. To date ...

Article GUID: 39624490


Effects of maternal mild hyperglycemia associated with snack intake on offspring metabolism and behavior across the lifespan

Author(s): Martins MG; Woodside B; Kiss ACI;

The increasing prevalence of diabetes is of particular concern in women of childbearing age because of the short and long-term consequences of maternal diabetes for the health of the offspring, such as a greater risk of developing metabolic impairments and cognitive deficits. In addition, maternal diet during pregnancy and lactation might contribute to ...

Article GUID: 38331375


Mismatch between calf paternity and observed copulations between male and female reindeer: Multiple mating in a polygynous ungulate?

Author(s): Coombs KR; Weladji RB; Holand Ø; Røed KH;

In polygynous systems, such as that exhibited by reindeer Rangifer tarandus, mate choice can be difficult to disentangle from male intrasexual competition because male behavior may constrain female choice. Multiple mating may provide an avenue for female mate choice, though it is difficult to identify using behavioral estimators alone. Molecular techniq ...

Article GUID: 37614915


The effects of circadian desynchronization on alcohol consumption and affective behavior during alcohol abstinence in female rats

Author(s): Meyer C; Schoettner K; Amir S;

Disruption of circadian rhythmicity distorts physiological and psychological processes and has major consequences on health and well-being. A chronic misalignment within the internal time-keeping system modulates alcohol consumption and contributes to stress-related psychiatric disorders which are known to trigger alcohol misuse and relapse. While there ...

Article GUID: 36620855


Modeling hormonal contraception in female rats: a framework for studies in behavioral neurobiology

Author(s): Lacasse JM; Gomez-Perales E; Brake WG;

Research on hormonal contraceptives (HC) in animal models is lacking, and as a result, so is our understanding of the impact of HC on the brain and behavior. Here, we provide a review of the pharmacology of HC, as well as the methodology and best practices for designing a model of HC in female rats. We outline specific methodological considerations rega ...

Article GUID: 35952797


Sex differences in developmental patterns of neocortical astroglia: A mouse translatome database

Author(s): Rurak GM; Simard S; Freitas-Andrade M; Lacoste B; Charih F; Van Geel A; Stead J; Woodside B; Green JR; Coppola G; Salmaso N;

Astroglial cells are key players in the development and maintenance of neurons and neuronal networks. Astroglia express steroid hormone receptors and show rapid responses to hormonal manipulations. However, despite important sex differences in the cortex and hippocampus, few studies have examin ...

Article GUID: 35108542


Joint intergroup aggression in female colobus monkeys (Colobus vellerosus) is associated with grooming bonds, male participation, and group size

Author(s): Wikberg EC; Gonzalez S; Rodriguez C; Sicotte P;

Cooperative home range defense is common in primates, despite a collective action problem that arises when group members benefit from winning the intergroup encounter regardless of whether they participate. The costs associated with this collective action problem may be mitigated by residing in small groups, residing with kin, or by forming strong bonds ...

Article GUID: 34927751


Cue-alcohol associative learning in female rats.

Author(s): Cofresí RU, Monfils MH, Chaudhri N, Gonzales RA, Lee HJ

The ability of environmental cues to trigger alcohol-seeking behaviors is believed to facilitate problematic alcohol use. We previously showed that the development of this cue-evoked alcohol approach reflects cue-alcohol learning and memory in the adult male rat; however, we do not know whether the same is true for similarly aged female rats. Consequent ...

Article GUID: 31002878


Genotype scores predict drug efficacy in subtypes of female sexual interest/arousal disorder: A double-blind, randomized, placebo-controlled cross-over trial.

Author(s): Tuiten A, Michiels F, Böcker KB, Höhle D, van Honk J, de Lange RP, van Rooij K, Kessels R, Bloemers J, Gerritsen J, Janssen P, de Leede L, Meyer JJ, Everaerd W, Frijlink HW, Koppeschaar HP, Olivier B, Pfaus JG

Womens Health (Lond). 2018 Jan-Dec;14:1745506518788970 Authors: Tuiten A, Michiels F, Böcker KB, Höhle D, van Honk J, de Lange RP, van Rooij K, Kessels R, Bloemers J, Gerritsen J, Janssen P, de Leede L, Meyer JJ, Everaerd W, Frijlink HW, Koppeschaar HP, Olivier B, Pfaus JG

Article GUID: 30016917


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